职业偷窃高手凯伦在一次行动中被捕入狱。出狱后，贼阿巴即找她合作，计划爆破国家银行，盗取保险库中的巨款。同时，贼阿巴又找来另一偷窃高手J.L.，一切部署完成后，两人旋即以熟练技巧打开保险库，当他们看到花花绿绿的银纸后，立即作出决定……Karen McCoy (Kim Basinger) is released from prison with nothing but the clothes on her back. Before being incarcerated Karen was the bank robber of her time, but now she wishes for nothing more than to settle down and start a new life. Unfortunately between a dirty parole officer, old business partners, and an idiot ex-husband she will have to do the unthinkable in order to save her son (Zack English) and new heart throb J.T. (Val Kilmer): another job.

一位名叫Juliette Flowers的女子发誓要把爱人Ransom Pride尸体从墨西哥运回位于德克萨斯的家。路上她不仅遇到了野蛮的赏金猎手，还遇到了凶残的牧师。幸好她有暹罗双胞胎，散弹枪矮人和Ransom的神枪手弟弟一路帮忙。

在20000英尺高的生命、死亡和戏剧中，SKYMED将紧张的角色旅程和高风险的医疗救援交织在一起，我们关注着加拿大北部偏远地区初露头角的护士和飞行空中救护车的飞行员的胜利、心碎和苦难。他们都是在他们的头上，靠自己，没有人可以依靠，但彼此。