Martin, an aging man, is abandoned in a psychiatric hospital, where a pharmaceutical business is conducting illegal drug tests. His granddaughter, Ana, discovers that her own father is directly involved and takes action into her own hands. As Ana and Martin run away to grant him his last wish, they must fight for their own survival against the vicious interests of the powerful ...

一对兄妹一起生活，维持着病态的亲密关系，暗示着彼此间有乱伦。不仅如此，这对兄妹还涉足其他更疯狂、令人作呕的事情，包括将活生生的小狗身上的肉割下来喂给自家的宠物狮子狗……

影片以意大利南部卡拉布里亚地区为背景，讲述了与黑手党组织光荣会相关的家族情仇。故事讲述鲁奇阿诺在乡间过着牧羊和种植蔬菜的农夫生活，刻意远离当地黑手党的血腥。多年前，同样务农的父亲被对立派谋杀。两个兄弟则选择了不同的道路..

一系列奇怪而可怕的事件发生在一位年轻女孩身上，她目睹了她的母亲因超自然力量而死亡。 召唤一位与另一位女孩有类似经历的医生，揭开了秘密和可怕的事件，导致了意想不到的结果。