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Former police detective Adrian Monk (Tony Shalhoub), whose photographic memory and amazing ability to piece together tiny clues made him a local legend, has suffered from intensified obsessive-compulsive disorder and a variety of phobias since the unsolved murder of his wife, Trudy, in 1997. Now on psychiatric leave from the San Francisco Police Department and working as a freelance detective/ consultant on difficult cases, Monk hopes to convince his former boss, Captain Leland Stottlemeyer (Ted Levine), to allow him to return to the force. Stottlemeyer, who wavered between admiration for Monk and annoyance at his eccentricities during the first season, is becoming more of a friend to Monk as the series develops, frequently calling him in to help, as much for Monk's benefit as for his own. However, he knows Monk's limitations as well as his strengths and may still harbor doubts about the wisdom of allowing Monk to carry a gun or subdue a perpetrator. Stottlemeyer's second-in-command, Lieutenant Randall Disher (Jason Gray-Stanford), also seems to be developing both admiration and compassion for the man he once labeled "the defective detective." Despite flaws and inadequacies all around, the three are becoming an increasingly effective team, with additional help from Monk's personal assistant. From the double-episode pilot through the first half of season three, Monk was aided by his nurse, Sharona Fleming (Bitty Schram). But in the tenth episode of the third season, Sharona was replaced by a new assistant, Natalie Teeger (Traylor Howard). Like Sharona, a divorcee with a son named Benjy, Natalie is a single parent, a widow with a daughter named Julie (Emmy Clarke). Unlike Sharona, Natalie is not a nurse but a former bartender with a fresh perspective on "Mr. Monk," as she still addresses her new boss.
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该剧改编自DC同名漫画书，故事背景设置在末日世界，一场大灾难导致男主之外的男性全部消亡，新世界的一切均由女性主宰。戴安·琳恩、巴里·基奥根饰一对母子。试播集导演梅丽娜·马苏卡斯(《无为大师》)。
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伊芙（塔拉·菲茨杰拉德 Tara Fitzgerald 饰）是法医研究基地的负责人，基地坐落在一个地处偏远的农场中，在这里，伊芙带领着她的团队，在尸体上积极探寻科学的奥秘。年轻有为的植物学家罗萨（乌米·马萨库 Wunmi Mosaku 饰）、血液分析师兼伊芙的旧情人麦克（马克·贝兹利 Mark Bazeley 饰）和深居简出的法医博士奥兹（芬莱·罗伯特森 Finlay Robertson 饰），每一位成员都为研究所的正常运作做出了巨大的贡献。 然而，尽管置身事外，但伊芙的研究基地还是受到了金融危机的影响，研究经费一再遭到削减，与此同时，为了节省开支，政府还下达了裁员的命令。在海尔警官的建议之下，伊芙决定同警方合作，参与凶杀案的调查和取证。尽管平日里早就习惯了冰冷沉默的尸体，然而，面对“新鲜火热”的凶杀现场，大家心里还是有种说不出的恐惧。
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Jackie, the heiress to her husband's fortune after his death, who finally finds love again with a plastic surgeon, Kevin. As tragedy continues around her, secrets about Kevin and her late husband's family nefariously come to light.
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Martin（基弗·萨瑟兰 Kiefer Sutherland 饰）因无法跟自己11岁的自闭儿子Jake（大卫·马宋兹 David Mazouz 饰）交流而烦恼，多次尝试都以失败告终。Jake总是面无表情，一整天独自捣腾报废的手机，通过拆解、摆弄零部件的方式来看这个世界 。 Jake的事例引起社工Clea（古古·姆巴塔-劳 Gugu Mbatha-Raw 饰）的注意。她拜访了Martin的家，指出Martin的全部生活已经被一个他再也无法控制的小孩所支配。决定要让政府来介入解决这个家庭问题。当Martin发现Jake拥有预见事情的能力，和掌握着连接任何事物的模式后，一切都改变了。实际上Jake一直在通过数字与人交流。现在Jake需要他的父亲Martin去破解这些数字的含义，似乎这些数字影响着他们的命运......
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本片为热门动画《开心汉堡店》的电影版。
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Amazon的《#律界巨人# Goliath》获在线媒体续订第三季，预定19年上线。第三季新增演员包括Dennis Quaid﹑Amy Brenneman﹑Beau Bridges﹑Griffin Dunne﹑Sherilyn Fenn及Shamier Anderson；于新季中，Billy McBride（#Billy Bob Thornton#饰）一位旧友突然死亡，这事件将令他面对新的「巨人」 - 中央谷地里一名富豪牧场主及他的妹妹（Dennis Quaid及Amy Brenneman饰演）。